Buy Pentapeptide-18 (Leuphasyl) 200mg Topical for Anti-Aging & Wrinkle Reduction Research
What is Pentapeptide-18 (Leuphasyl)?
Pentapeptide-18, also known as Leuphasyl, is a cosmetic-grade peptide designed for research into anti-aging, wrinkle reduction, and muscle relaxation effects on the skin.
It functions by modulating neurotransmitter release, similar to Botox-like mechanisms, helping reduce the depth of expression wrinkles.
Leuphasyl is often studied in combination with Argireline (Acetyl Hexapeptide-8) for enhanced topical anti-wrinkle activity.
Our Pentapeptide-18 (Leuphasyl) 200mg is formulated at 99% purity for advanced cosmetic and dermatological research.
How Does Pentapeptide-18 Work?
Leuphasyl targets SNARE complex-associated proteins, which are responsible for muscle contractions that form wrinkles.
By influencing enkephalin receptor binding in neuromuscular junctions, Pentapeptide-18 can inhibit neurotransmitter release—reducing muscle cell excitability.
This leads to relaxation of facial tension areas, particularly around the forehead, eyes, and mouth in topical formulations.
In combination studies, Pentapeptide-18 enhances the efficacy of Argireline, making it a synergistic peptide in anti-aging skincare formulations.
Key Research Benefits of Pentapeptide-18 (Leuphasyl)
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Reduces the appearance and depth of facial wrinkles
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Promotes muscle relaxation in targeted areas
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Aids in studying Botox-like mechanisms via peptide pathways
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Improves skin smoothness and elasticity
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May support collagen remodeling and hydration retention
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Enhances effectiveness of multi-peptide anti-aging formulas
⚠️ For research and topical formulation use only. Not approved for human or therapeutic application.
Product Specifications
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Product Name: Pentapeptide-18 (Leuphasyl) 200mg (Topical)
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Category: Cosmetic Peptides / Anti-Aging Research
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Form: Lyophilized powder
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Purity: ≥99% (HPLC tested)
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Molecular Formula: C₂₇H₄₈N₆O₈
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Molecular Weight: 584.71 g/mol
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Storage: Store refrigerated (2–8°C), dry and away from direct light
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Shelf Life: 24 months (unopened, under proper conditions)
Each vial is independently tested and certified for research-grade integrity.
Handling and Application Guidelines
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For research or formulation testing only
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Reconstitute with sterile, distilled water or topical carrier solution
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Use in controlled environments with standard laboratory procedures
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Do not inject or ingest
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Maintain aseptic handling to ensure purity
Safety and Precautions
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Not intended for human or animal use
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Avoid direct skin contact outside of approved lab studies
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Always wear protective equipment (lab coat, gloves, eye protection)
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Dispose of unused product following local regulations
Mechanism of Action Overview
Pentapeptide-18 mimics the natural enkephalin pathways of the skin, binding to receptors that inhibit the release of acetylcholine, a neurotransmitter that triggers muscle contraction.
This biological interaction provides a non-invasive mechanism for studying wrinkle reduction comparable to neurotoxin effects, but through a peptide-based topical approach.
Quality Assurance
Peptide Online Store ensures that every vial of Leuphasyl 200mg meets strict GMP and ISO 9001 quality standards, supported by:
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HPLC & MS purity validation
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Endotoxin-free certification
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Batch traceability and documentation
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Third-party independent testing
Research Applications
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Anti-aging skincare formulation development
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Neuromodulating peptide research
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Studies on facial expression wrinkle reduction
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Investigations into peptide synergy (Leuphasyl + Argireline)
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Topical bioavailability and peptide penetration testing
Why Choose Peptide Online Store for Pentapeptide-18 (Leuphasyl)?
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≥99% certified purity
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Competitive pricing and global shipping
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Independent third-party lab verification
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Trusted by dermatological and cosmetic researchers worldwide
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Secure packaging to maintain molecular stability
Shipping & Storage
Peptides are shipped in temperature-controlled, moisture-resistant packaging to preserve stability during transit.
Worldwide tracked and discreet shipping is available.
Recommended to store at 2–8°C immediately upon arrival.
How to Order Pentapeptide-18 Online
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Visit peptideonlinestore.com
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Find Pentapeptide-18 (Leuphasyl) 200mg under Cosmetic Peptides
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Add to cart and proceed to checkout
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Choose your preferred shipping and payment method
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Receive confirmation and tracking within 24–48 hours
Frequently Asked Questions (FAQ)
Q: Is Pentapeptide-18 similar to Botox?
A: While not identical, Leuphasyl acts on similar neuromuscular pathways that relax facial muscles—making it a topical peptide alternative for research.
Q: Can Pentapeptide-18 be used in finished skincare products?
A: It is designed only for R&D and formulation testing. Commercial cosmetic use requires proper certification and safety assessment.
Q: Can I combine it with other peptides?
A: Yes, it’s commonly studied with Argireline (Acetyl Hexapeptide-8) and Matrixyl (Palmitoyl Pentapeptide-4) for synergistic results.
Related Peptides
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Argireline (Acetyl Hexapeptide-8) – Neurotransmitter-inhibiting peptide
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Matrixyl (Palmitoyl Pentapeptide-4) – Collagen-boosting peptide
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Syn-Ake (Dipeptide Diaminobutyroyl Benzylamide Diacetate) – Muscle relaxant mimic peptide
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Palmitoyl Tetrapeptide-7 (Rigin) – Skin elasticity and anti-inflammation support
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Copper Peptide GHK-Cu – Collagen regeneration and wound healing peptide
Final Thoughts
Pentapeptide-18 (Leuphasyl) 200mg represents a scientifically advanced cosmetic peptide for exploring non-invasive wrinkle reduction and skin relaxation mechanisms.
Its proven efficacy in reducing expression lines makes it a benchmark compound for topical anti-aging peptide research.
At Peptide Online Store, we ensure exceptional purity, global availability, and comprehensive documentation — supporting cosmetic scientists and peptide researchers worldwide.

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